An accurate diagnosis may also help to control outbreaks, reduce potential antibiotic resistance and facilitate a more rapid patient recovery.
Early, rapid and specific detection of the virus or bacteria involved using real-time PCR methods is essential to provide patient-tailored therapy for better outcomes. What are the benefits of Respiratory pathogens molecular testing?Ĭlinical symptoms for different respiratory illnesses are similar so in vitro diagnostic molecular methods are necessary to determine the causative agents. However, young children, the elderly, immunocompromised or weakened individuals (including those with chronic disease, cancer, or in intensive care) are most likely to suffer serious and potentially life-threatening pneumopathies. Others pathogens such as Coronaviruses, Bocaviruses, Enteroviruses, Parainfluenza 4, Human Metapneumovirus, Mycoplasma pneumonia and Chlamydophila pneumoniae also infect the respiratory tract and can cause various diseases from mild self-limiting upper respiratory infections to potentially threatening pneumonia.Īnyone can become infected and ill with these respiratory pathogens. In both children and adults, acute respiratory infections (ARI) are most frequently due to infections with Influenza A and B viruses, Parainfluenza viruses 1, 2 and 3, Respiratory Syncytial Virus (RSV A and B), Adenoviruses and Rhinoviruses. The vast majority of respiratory illnesses are caused by viruses and bacteria. Xu M., Qin X., Astion M.L., Rutledge JC., Simpson J., Jerome KR., Englund J.A., Zerr D.M., Migita R.T., Rich S., Childs J.C., Cent A., Del Beccaro M.A.ĪMERICAN JOURNAL OF CLINICAL PATHOLOGY 2013 139(1):118-23 Implementation of FILMARRAY® Respiratory Viral Panel in a Core Laboratory Improves Testing Turnaround Time and Patient Care. Seasonality and Prevalence of Respiratory Pathogens detected by multiplex PCR at a Tertiary Care Medical Center. Rogers B.B., Shankar P., Jerris R.C., Kotzbauer D., Anderson E.J., Watson JR., O'Brien L.A., Uwindatwa F, McNamara K, Bost J.E.ĪRCHIVES OF PATHOLOGY & LABORATORY MEDICINE 2015 139(5):636-41 Impact of a Rapid Respiratory Panel Test on Patient Outcomes. JOURNAL OF MEDICAL MICROBIOLOGY 2015 64:312-313 Pettit N., Matushek S., Charnot-Katsikas A., Tesic V., Boonlayangoor S., Brielmaier B., Pisano J.
#Biofire diagnostics plus#
The BIOFIRE ® FILMARRAY ® Respiratory 2.1 plus Panel is incredibly comprehensive, with simultaneous testing for 23 of the most common pathogens, including SARS-CoV-2, involved in RTI. BIOFIRE ® FILMARRAY ® Pneumonia plus Panel.Taken together, the five BIOFIRE ® FILMARRAY ® panels comprise the largest infectious disease pathogen menu commercially available. Comprehensive: 23 target respiratory panelīIOFIRE ® FILMARRAY ® Respiratory 2.1 plus Panel is one of five FDA-cleared and/or CE-marked panels for use on the BIOFIRE ® FILMARRAY ® multiplex PCR system.Easy: No precise measuring or pipetting required.Rapid and accurate identification of the causative agent of upper respiratory tract infections may improve patient management by informing timely and effective antibiotic or antiviral therapy, preventing secondary spread of infection, shortening hospital stays and reducing costs of unnecessary ancillary tests. BIOFIRE ® FILMARRAY ® integrates sample preparation, amplification, detection and analysis into one simple system that requires just 2 minutes of hands-on time, with a total run time of about an hour. It works on the BIOFIRE ® FILMARRAY ® 2.0 and Torch systems, an FDA, CE-IVD, and TGA certified multiplex PCR system. The BIOFIRE ® Respiratory 2.1 plus Panel tests for 19 viruses and 4 bacteria which cause respiratory tract infections with an overall sensitivity and specificity of 97,4% and 99,4% respectively. Simple, comprehensive respiratory testing
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